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Since polymerase gamma is the mitochondrial polymerase replicating mitochondrial DNA (mtDNA), its inhibition can introduce mtDNA mutations which then induce mitochondrial dysfunction or results in a decrease in overall mtDNA levels

doi: 10.1186/s13046-019-1413-7 76 WangLZhangZLiMWangFJiaYZhangFet al

One key culprit is the equalization (EQ) line , a large-diameter pipe designed to balance water levels among multiple tower sumps

Therefore, ASCL1 expression can serve as a marker of ferroptosis resistance in fully NE differentiated human SCLC, yet its isolated expression is insufficient to drive cell fate switch in our cellular system and along with that ferroptosis resistance

In addition, Portulaca shows significant down-regulation of aquaporins ( TIP1-1 , TIP2-1 , and PIP2-7 ), which prevent excessive water loss by reducing water permeability, thereby maintaining cellular osmotic balance under salinity stress (Boursiac et al

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