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13 The GI mucosa and immune cells also significantly contribute to free radical production, particularly in conditions of increased mucosal defense and inflammation

and Ingold, K.U

Examples of MUE are illustrated in Figure 9-4

Il conduit galement une dtoxification cellulaire pour maintenir la sant cellulaire

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

These processes occur when there is an imbalance between lipid oxidation and the antioxidant system, leading to cell rupture and death and eventually ferroptosis ( Enzymatic Lipid Peroxidation Enzymatic lipid peroxidation is mainly mediated by the lipoxygenase (LOX) family, which is a group of haeme-type iron-containing enzymes that catalyse PUFAs, primarily adrenergic acid (Ada) and arachidonic acid (AA)