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This will allow us to determine the correlation of the in vitro results with the actual in vivo responses

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Although further research is required in order to better understand its mechanisms and efficacy in practical settings, BPC 157 has the potential to be developed as a new therapy to conservatively treat or aid recovery following surgery in typically hypovascular and hypocellular soft tissues such as tendon and ligament tissue

The study only employed a single drug dose, overlooking dose-dependent investigations, which will also be addressed in subsequent research

Consistent with the phosphorylation of Met and the subsequent signalling proteins, the dimeric macrocycles are able to clearly mimic the functional role of hHGF and induce cellular responses in not only model cell lines but also various normal human cells (Figs 4, 5, 6 and Supplementary Figs 13 and 14)

Its evidence base is genuinely strong for a trial-stage product two large Phase 3a randomized controlled trials plus a Phase 1b pharmacology study but it has not received marketing approval from any regulator, and its complete benefitrisk profile is still being evaluated