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Enzymatic defenders form a formidable internal defense against the onslaught of oxidation, but this natural protective mechanism can be disrupted by the increasingly common factors of poor dietary choices, pollution, stress, and overuse of antibiotics, leading to a diminished capacity to fend off oxidative damage

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Akkermansia muciniphila comprises 3%5% of mouse gut microbiota but only 1%3% in humans (51)

The core mechanism of action of epicatechin is the inhibition of myostatin, which belongs to the transforming growth factor- (TGF-) superfamily and acts as an endogenous negative regulator of skeletal muscle mass

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The appearance of autoantibodies and clinical manifestations of autoimmune disease, including vitiligo, have been associated with statistically significant improvements in overall survival rates for patients with cutaneous melanoma