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doi: 10.1128/mBio.01828-17 270 MayR

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Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis

L., & Bjerre, M

If methylation is congested, the correct strategy is to: Support SAH clearance Reduce oxidative stress Use magnesium, zinc, and B6 Avoid aggressive methyl donors This pattern is common in patients with inflammation or mitochondrial impairment