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Embryos with optimal cleavage timing show coordinated expression of cell cycle genes and metabolic regulators, while delayed development correlates with altered gene expression patterns and metabolic dysfunction [433, 434]

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Rats with acute pancreatitis had a 21% reduction in cardiac output, a 37% decrease in contractility, a 23% decline in diastolic tension, and a twofold increase in the cardiac tissue edema index [80]

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