glutathione s transferase in pgex Roles for transferases plant secondary metabolism Overexpression of Glutathione S-Transferases in

BMJ 367:l6217

Burke MA, Ardehali H: Mitochondrial ATP-binding cassette proteins

This finding agrees with the literature whereby the role of quinone redox metabolism is an ambiguous source of toxicity, with evidence suggesting that redox cycling requires supra-pharmacological concentrations of doxorubicin to generate substantial ROS in tissues and cells 10

Anal Biochem 72:248254

Preclinical models converge on immuneinflammatory signaling, HPA axis dysregulation and neurotransmitter alterations as recurrent mechanistic pathways (Ravi et al., 2021

Research suggests that the T allele is associated is marked reduction in the activity of the GPx1 enzyme, with some studies showing a 40% reduction in GPx1 activity