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Description

Gene Set Enrichment Analysis (GSEA), as implemented in the R/Bioconductor package clusterProfiler (v 4.4.4), was used to search for modulated pathways of WikiPathways database ( Mutation profiles, comprising SNV and CNV (amplifications and homozygous deletions) and their frequencies, for the KEAP1 , NRF2 and CUL3 genes were downloaded from cBioportal for all 28 studies forming the TCGA PanCancer dataset

Harle DG, Baldo BA, Wells JV

Additionally, the accumulation of heavy metals in biological systems raises concerns regarding long-term biocompatibility and potential mutagenicity

Daviglus E, et al

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