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The NPs (10 L, 2.5 mg kg 1 ) and PBS (10 L) were delivered by intra-articular injection into the right knee of the OA mice at 4 weeks and 6 weeks post-surgery, respectively

There is no strong evidence that it causes weight gain directly

Mitochondrial genotype associated with longevity

Contact your GP for B12 testing if you have: Symptoms suggesting deficiency (persistent fatigue, pins and needles, memory problems, glossitis) Risk factors for deficiency (vegan diet, gastric surgery, long-term metformin or proton pump inhibitor use) [1] [4] Concerns about whether your current supplementation dose is appropriate Underlying conditions affecting B12 metabolism (kidney disease, liver disease) Unexplained high B12 levels on a blood test when not taking supplements Routine monitoring is essential for patients receiving therapeutic B12 injections

For individuals who are deficient in this essential vitamin, injections provide a fast and effective way to replenish B12 stores and support overall health

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