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Radtke KK, Coles LD, Mishra U, Orchard PJ, Holmay M, Cloyd JC

Dose adjustments depend on clinical markers including skin thickness, collagen expression indicators, and localized tissue response at injection sites

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Thereby, a large number of PLGA nanoparticles loaded with antitumor drugs possessing consistent sizes were successfully produced, which promotes the stability and production volume of nanodrug carriers and reduces the cost of production wastage