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and PIPE-791 has been shown to inhibit neuroinflammation and treat MS

"Neuroimaging in chronic fatigue syndrome"

10.1159/000366375 46 HoltJ

(B-F) After 24h in culture with either 250uM melatonin or vehicle control the concentrations of IL-5 (B), IL-13 (C) , IL-9 (D) IL-10 (E) , and IL-6 (F) was determined by LEGENDPlex assay