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Glutaredoxin carries out GSH-dependent reduction in proteins of oxidized cysteine residues (Cys SOH, Cys SO2H), mediated and intermolecular disulfide bonds (-S-S-) to the redox-active thiol state (Ren et al., 2017)

Chem Asian J

To control the genes to start or stop being expressed, we need a regulatory system

Research has shown that, when the concentration of antioxidants in the human body is above the necessary threshold, oxidative effects are increased

Trypsin without proline restriction cleavage option was used, with one allowed miscleavage and peptide length range set to 730 amino acids

Statistical Analysis All statistical analyses were conducted applying GraphPad Prism 8.0 software (GraphPad Software, USA)