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With real-world use, many patients experience remarkable results: up to 20% or more body weight reduction in months when paired with nutrition and exercise

And its also possible to utilize both methods as part of the same treatment

Clinical trials showed significant weight loss at every dose level, with 5mg producing an average of 16% body weight reduction in the SURMOUNT-1 trial

However, this process is non-selective and influenced by regional differences in receptor density, blood flow, and hormonal sensitivity