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This overexpression is further associated with aggressive metastasis, higher rates of tumor recurrence, and worse prognoses [22]

Several studies point to the fact that supplementation with magnesium can have positive effects on the severity of the tinnitus: A study separated patients with sudden acute hearing loss, with no discernible cause, into two groups

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Furthermore, since research indicates that bipolar disorder is a progressive illness, possibly characterized by disparate pathophysiologic substrates in different phases of illness, one can make a case for stratifying the sample based base on the stage of the illness (85, 86)

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