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therefore, compared to in vivo conditions, higher levels of cystine in standard cell culture media drive more SLC7A11-mediated cystine uptake and glutamate export, resulting in more glutamine dependency and more cellular sensitivity to glutaminase inhibition (Muir et al., 2017)

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Children younger than 5 are the only age group not yet eligible for vaccination against Covid-19

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In human MASLD patients, serum 2-OG levels in grade II and III hepatic steatosis patients are significantly higher than those in healthy subjects, suggesting that circulating 2-OG acts as a potential predictive biomarker for hepatic steatosis