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Peer review Peer review information Nature Plants thanks Steffen Abel and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Donnelly S, Haslett C, Reid P, Grant I, Wallace W, Metz C, Bruce L, Bucala R

Although the beneficial effects of probiotics, certain metabolites, and FMT on migraine and other neurological disorders favor this concept, there are major gaps in understanding their etiology and pathogenesis, and it is not yet clear which of the microbiome related neurotransmitters, metabolites, and pathways are causally involved