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Mitochondria dynamically redistribute within neurons in response to local energy needs, often clustering near synaptic terminals during periods of high activity to meet localized energy demands (85)

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Conversion of homocysteine to methionine occurs in the cell cytoplasm by the enzyme methionine synthase, which requires methylcobalamin as a cofactor, resulting in an accumulation of homocysteine in plasma if there is no B12

2006 Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy.[BMC Pediatr